Journal: Infection and Drug Resistance

Article Title: Hybridization and antibiotic synergism as a tool for reducing the cytotoxicity of antimicrobial peptides

doi: 10.2147/IDR.S166236

Figure Lengend Snippet: MICs of H4 against all the microbial strains employed in this study

Article Snippet: The most sensitive strain to H4’s activity was the Gram-negative K. pneumoniae (ATCC 13883) with an MIC value of 2.5 μM, while the most resistant strain being the MDR P. aeruginosa (ATCC BAA2114) strain with an MIC value of 25 μM.

Techniques:

Journal: Infection and Drug Resistance

Article Title: Hybridization and antibiotic synergism as a tool for reducing the cytotoxicity of antimicrobial peptides

doi: 10.2147/IDR.S166236

Figure Lengend Snippet: MICs of individual antibiotics and those in combination with H4 including the percentage reduction of antibiotic MIC when in combination; MICs of individual H4 and those in antibiotic combination; and the FIC indices for the antimicrobial combinations against the tested bacterial species

Article Snippet: The most sensitive strain to H4’s activity was the Gram-negative K. pneumoniae (ATCC 13883) with an MIC value of 2.5 μM, while the most resistant strain being the MDR P. aeruginosa (ATCC BAA2114) strain with an MIC value of 25 μM.

Techniques:

Journal: Infection and Drug Resistance

Article Title: Hybridization and antibiotic synergism as a tool for reducing the cytotoxicity of antimicrobial peptides

doi: 10.2147/IDR.S166236

Figure Lengend Snippet: Antibiofilm activity of H4 against standard resistant strains of Staphylococcus aureus (BAA41) and Pseudomonas aeruginosa (BAA2114)

Article Snippet: The most sensitive strain to H4’s activity was the Gram-negative K. pneumoniae (ATCC 13883) with an MIC value of 2.5 μM, while the most resistant strain being the MDR P. aeruginosa (ATCC BAA2114) strain with an MIC value of 25 μM.

Techniques: Activity Assay

Journal: Antibiotics

Article Title: Recent Progress in the Development of Small-Molecule FtsZ Inhibitors as Chemical Tools for the Development of Novel Antibiotics

doi: 10.3390/antibiotics8040217

Figure Lengend Snippet: Minimum inhibitory concentrations of the quinolinium and structurally related compounds.

Article Snippet: This compound also showed very promising antibacterial results against Gram-negative strains such as E. coli ATCC 25922, A. baumannii ATCC 19606, P. aeruginosa ATCC BAA-2108, and K. pneumoniae ATCC BAA-2470 with MIC values of 1.54, 12.31, 6.16, and 12.31 μM, respectively.

Techniques:

Journal: Antibiotics

Article Title: Recent Progress in the Development of Small-Molecule FtsZ Inhibitors as Chemical Tools for the Development of Novel Antibiotics

doi: 10.3390/antibiotics8040217

Figure Lengend Snippet: MIC values of tiplaxtinin ( 62 ) on Gram-positive and Gram-negative bacteria.

Article Snippet: This compound also showed very promising antibacterial results against Gram-negative strains such as E. coli ATCC 25922, A. baumannii ATCC 19606, P. aeruginosa ATCC BAA-2108, and K. pneumoniae ATCC BAA-2470 with MIC values of 1.54, 12.31, 6.16, and 12.31 μM, respectively.

Techniques: Bacteria

Journal: Molecules

Article Title: Discovery of New Schiff Bases Tethered Pyrazole Moiety: Design, Synthesis, Biological Evaluation, and Molecular Docking Study as Dual Targeting DHFR/DNA Gyrase Inhibitors with Immunomodulatory Activity

doi: 10.3390/molecules25112593

Figure Lengend Snippet: In vitro antimicrobial activities of the most promising Schiff bases against multidrug-resistant bacteria (MDRB).

Article Snippet: The synthesized pyrazole Schiff bases 6b , 7b , 7c , 8a , 8d , and 9b were tested for their in vitro antibacterial activity against a panel of multidrug-resistant bacteria (MDRB) classified as one clinical strain S. aureus (ATCC 43300) (MRSA) with three standard strain S. aureus (ATCC 33591), E. coli (ATCC BAA-196), and P. aeruginosa (ATCC BAA-2111).

Techniques: In Vitro, Bacteria, Inhibition

Journal: Molecules

Article Title: Discovery of New Schiff Bases Tethered Pyrazole Moiety: Design, Synthesis, Biological Evaluation, and Molecular Docking Study as Dual Targeting DHFR/DNA Gyrase Inhibitors with Immunomodulatory Activity

doi: 10.3390/molecules25112593

Figure Lengend Snippet: Minimal inhibitory concentrations (MIC, µg/mL) and minimum bactericidal concentrations (MBC, µg/mL) of the most potent Schiff bases against MDRB.

Article Snippet: The synthesized pyrazole Schiff bases 6b , 7b , 7c , 8a , 8d , and 9b were tested for their in vitro antibacterial activity against a panel of multidrug-resistant bacteria (MDRB) classified as one clinical strain S. aureus (ATCC 43300) (MRSA) with three standard strain S. aureus (ATCC 33591), E. coli (ATCC BAA-196), and P. aeruginosa (ATCC BAA-2111).

Techniques: